Difference between Double Marker Test and Quadruple Test
Various prenatal tests can be administered to pregnant women to screen for different birth defects. One such test is the Quadruple Marker Test, and the other prenatal test is the Double Marker Test. They work towards the same objective but are different from one another. So, what is the difference between these two tests?
This blog post will discuss the differences between the Quadruple Marker and Double Marker tests. Read on to know the difference.
An Overview of Double Marker Test
The Double Marker Test is a blood test usually performed between the 11th and 13th weeks of pregnancy. It screens for two different conditions: Down Syndrome and Edwards Syndrome. The Double Marker Test is less accurate than the Quadruple Marker Test and is less expensive.
Human chorionic gonadotrophin (hCG) & PAPP-A (pregnancy-associated plasma protein) are two markers measured in the blood test. In contrast, an NT scan measures the fluid beneath the skin behind the baby’s neck. The results of these two tests are used to determine whether a kid has Down syndrome.
The results would indicate aberrant levels of PAPP-A and hCG and a more excellent NT scanning value if there was a possibility of Down’s syndrome.
An Overview of Quadruple Marker Test
The Quadruple Marker Test is a blood test usually performed between the 15th and 20th weeks of pregnancy. It screens for four different conditions: Down Syndrome, Edwards Syndrome, Patau Syndrome, and Neural Tube Defects. The Quadruple Marker Test is more accurate than the Double Marker Test and more expensive.
A mother is typically advised to undergo a quadruple marker test because it is more precise than a double marker test in identifying genetic abnormalities in the fetus. Four blood markers, including b-hCG (beta subunit of human chorionic gonadotrophin), uEst (unconjugated estriol), AFP (serum alpha-fetoprotein), and Inhibin A, are tested in a quadruple marker test price.
If you risk having a child with Down syndrome, your hCG levels will be high, and your AFP & uEst levels might be low.
Difference Between Double Marker Test and Quadruple Test
The main difference between the two tests is that the Quadruple Marker Test screens for four conditions while the Double Marker Test screens for two. In addition, the Quadruple Marker Test is more accurate than the Double Marker Test. Other than this, the two tests are similar because they are both blood tests performed during pregnancy.
When it comes to cost, the Quadruple Marker Test is more expensive than the Double Marker Test. Therefore, you should discuss with your doctor which test is right for you.
The Bottom Line
The Double Marker Test and Quadruple Test are both crucial tests that can help you determine the health of your pregnancy. The Quadruple Test is a more comprehensive test that can provide more information about your pregnancy. Consult your doctor for the test ideal for you.